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1

Exaggerated Activation of Dorsal Anterior Cingulate Cortex During Cognitive Interference: A Monozygotic Twin Study of Posttraumatic Stress Disorder

Shin, Lisa M., Bush, George, Milad, Mohammed R., Lasko, Natasha B., Brohawn, Kathryn Handwerger, Hughes, Katherine C., Macklin, Michael L., Gold, Andrea L., Karpf, Rachel D., Orr, Scott P., Rauch, Sco

Journal:

American Journal of Psychiatry

Year:

2011

Language:

english

File:

PDF, 801 KB

english, 2011

2

Integrating Genomics into Drug Discovery and Development: Challenges and Aspirations

Raja, Rajiv, Lee, Young S., Streicher, Katie, Conway, James, Wu, Song, Sridhar, Sriram, Kuziora, Mike, Liu, Hao, Higgs, Brandon W., Brohawn, Philip Z., Bais, Carlos, Jallal, Bahija, Ranade, Koustubh

Journal:

Pharmaceutical Medicine

Year:

2017

Language:

english

File:

PDF, 877 KB

english, 2017

3

The Neural Correlates of Emotional Memory in Posttraumatic Stress Disorder

Kathryn Handwerger Brohawn, Reid Offringa, Danielle L. Pfaff, Katherine C. Hughes, Lisa M. Shin

Journal:

Biological Psychiatry

Year:

2010

Language:

english

File:

PDF, 1.21 MB

english, 2010

4

Anifrolumab, an Anti-Interferon-Alpha Receptor Monoclonal Antibody, in Moderate to Severe Systemic Lupus Erythematosus

Furie, Richard, Khamashta, Munther, Merrill, Joan T., Werth, Victoria P., Kalunian, Kenneth, Brohawn, Philip, Illei, Gabor G., Drappa, Jorn, Wang, Liangwei, Yoo, Stephen

Journal:

Arthritis & Rheumatology

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

5

RNA-seq Analyses Reveal that Cervical Spinal Cords and Anterior Motor Neurons from Amyotrophic Lateral Sclerosis Subjects Show Reduced Expression of Mitochondrial DNA-Encoded Respiratory Genes, and rhTFAM May Correct This Respiratory Deficiency.

Ladd, Amy C., Brohawn, David G., Thomas, Ravindar R., Keeney, Paula M., Berr, Stuart S., Khan, Shaharyar M., Portell, Francisco R., Shakenov, Meiram Zh., Antkowiak, Patrick F., Kundu, Bijoy, Tustison,

Journal:

Year:

2017

Language:

english

File:

PDF, 3.69 MB

english, 2017

6

Type I interferon gene signature test–low and –high patients with systemic lupus erythematosus have distinct gene expression signatures

Brohawn, PZ, Streicher, K, Higgs, B W, Morehouse, C, Liu, H, Illei, G, Ranade, K

Journal:

Year:

2019

Language:

english

File:

PDF, 838 KB

english, 2019

7

Neutralization of interferon-α/β–inducible genes and downstream effect in a phase I trial of an anti–interferon-α monoclonal antibody in systemic lupus erythematosus

Yihong Yao, Laura Richman, Brandon W. Higgs, Christopher A. Morehouse, Melissa de los Reyes, Philip Brohawn, Jianliang Zhang, Barbara White, Anthony J. Coyle, Peter A. Kiener, Bahija Jallal

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 1004 KB

english, 2009

8

MTHFR 677C>T effects on anterior cingulate structure and function during response monitoring in schizophrenia: a preliminary study

Joshua L. Roffman, David G. Brohawn, Jesse S. Friedman, Kara A. Dyckman, Katharine N. Thakkar, Yigal Agam, Mark G. Vangel, Donald C. Goff, Dara S. Manoach

Journal:

Brain Imaging and Behavior

Year:

2011

Language:

english

File:

PDF, 461 KB

english, 2011

9

Molecular architecture of the Nup84–Nup145C–Sec13 edge element in the nuclear pore complex lattice

Brohawn, Stephen G, Schwartz, Thomas U

Journal:

Nature Structural and Molecular Biology

Year:

2009

Language:

english

File:

PDF, 639 KB

english, 2009

10

A novel oncogenic role for the miRNA-506-514 cluster in initiating melanocyte transformation and promoting melanoma growth

Streicher, K L, Zhu, W, Lehmann, K P, Georgantas, R W, Morehouse, C A, Brohawn, P, Carrasco, R A, Xiao, Z, Tice, D A, Higgs, B W

Journal:

Year:

2011

Language:

english

File:

PDF, 2.17 MB

english, 2011

11

Seasonal distribution of total and pathogenic Vibrio parahaemolyticus in Chesapeake Bay oysters and waters

Salina Parveen, Kumidini A. Hettiarachchi, John C. Bowers, Jessica L. Jones, Mark L. Tamplin, Rusty McKay, William Beatty, Kathy Brohawn, Ligia V. DaSilva, Angelo DePaola

Journal:

International Journal of Food Microbiology

Year:

2008

Language:

english

File:

PDF, 566 KB

english, 2008

12

Corrigendum to “Seasonal distribution of total and pathogenic Vibrio parahaemolyticus in Chesapeake Bay oysters and waters” [Int. J. of Food Microbiol. 128 (2008) 354–361]

Salina Parveen, Kumidini A. Hettiarachchi, John C. Bowers, Jessica L. Jones, Mark L. Tamplin, Rusty McKay, William Beatty, Kathy Brohawn, Ligia V. DaSilva, Angelo DePaola

Journal:

International Journal of Food Microbiology

Year:

2009

Language:

english

File:

PDF, 63 KB

english, 2009

13

The Structure of the Scaffold Nucleoporin Nup120 Reveals a New and Unexpected Domain Architecture

Nina C. Leksa, Stephen G. Brohawn, Thomas U. Schwartz

Journal:

Year:

2009

Language:

english

File:

PDF, 1.33 MB

english, 2009

14

The Nuclear Pore Complex Has Entered the Atomic Age

Stephen G. Brohawn, James R. Partridge, James R.R. Whittle, Thomas U. Schwartz

Journal:

Year:

2009

Language:

english

File:

PDF, 1.46 MB

english, 2009

15

New Water-Soluble Phosphines as Reductants of Peptide and Protein Disulfide Bonds: Reactivity and Membrane Permeability†

Cline, Daniel J., Redding, Sarah E., Brohawn, Stephen G., Psathas, James N., Schneider, Joel P., Thorpe, Colin

Journal:

Year:

2004

Language:

english

File:

PDF, 357 KB

english, 2004

16

Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway

Higgs, B. W., Liu, Z., White, B., Zhu, W., White, W. I., Morehouse, C., Brohawn, P., Kiener, P. A., Richman, L., Fiorentino, D., Greenberg, S. A., Jallal, B., Yao, Y.

Journal:

Annals of the Rheumatic Diseases

Year:

2011

Language:

english

File:

PDF, 501 KB

english, 2011

17

Genetic Variation Throughout the Folate Metabolic Pathway Influences Negative Symptom Severity in Schizophrenia

Roffman, J. L., Brohawn, D. G., Nitenson, A. Z., Macklin, E. A., Smoller, J. W., Goff, D. C.

Journal:

Schizophrenia Bulletin

Year:

2013

Language:

english

File:

PDF, 242 KB

english, 2013

18

Diminished rostral anterior cingulate cortex activation during trauma-unrelated emotional interference in PTSD

Reid Offringa, Kathryn Handwerger Brohawn…

Journal:

Biology of Mood & Anxiety Disorders

Year:

2013

Language:

english

File:

PDF, 328 KB

english, 2013

19

Genomic Biomarkers for Pharmaceutical Development || Translating Biomarker Discovery into Companion Diagnostics through Validation and Regulatory Consideration

Brohawn, Philip

Year:

2014

Language:

english

File:

PDF, 1.04 MB

english, 2014

20

Crystal Structure of the Human K2P TRAAK, a Lipid- and Mechano-Sensitive K+ Ion Channel

Brohawn, S. G., del Marmol, J., MacKinnon, R.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.82 MB

english, 2012

21

Low frequency KRAS mutations in colorectal cancer patients and the presence of multiple mutations in oncogenic drivers in non-small cell lung cancer patients

Jiang, Liyan, Huang, Jiaqi, Morehouse, Chris, Zhu, Wei, Korolevich, Susana, Sui, Dan, Ge, Xiaoxiao, Lehmann, Kim, Liu, Zheng, Kiefer, Christine, Czapiga, Meggan, Su, Xinying, Brohawn, Philip, Gu, Yi,

Journal:

Cancer Genetics

Year:

2013

Language:

english

File:

PDF, 1.05 MB

english, 2013

22

Development and validation of a predictive model for the growth of Vibrio parahaemolyticus in post-harvest shellstock oysters

Parveen, Salina, DaSilva, Ligia, DePaola, Angelo, Bowers, John, White, Chanelle, Munasinghe, Kumudini Apsara, Brohawn, Kathy, Mudoh, Meshack, Tamplin, Mark

Journal:

International Journal of Food Microbiology

Year:

2013

Language:

english

File:

PDF, 410 KB

english, 2013

23

Increased IR-A/IR-B ratio in non-small cell lung cancers associates with lower epithelial-mesenchymal transition signature and longer survival in squamous cell lung carcinoma

Jiang, Liyan, Zhu, Wei, Streicher, Katie, Morehouse, Chris, Brohawn, Philip, Ge, Xiaoxiao, Dong, Zhengwei, Yin, Xiaolu, Zhu, Guanshan, Gu, Yi, Ranade, Koustubh, Higgs, Brandon W, Yao, Yihong, Huang, J

Journal:

Year:

2014

Language:

english

File:

PDF, 633 KB

english, 2014

24

Inhibition of Myogenic MicroRNAs 1, 133, and 206 by Inflammatory Cytokines Links Inflammation and Muscle Degeneration in Adult Inflammatory Myopathies

Georgantas, Robert W., Streicher, Katie, Greenberg, Steven A., Greenlees, Lydia M., Zhu, Wei, Brohawn, Philip Z., Higgs, Brandon W., Czapiga, Meggan, Morehouse, Christopher A., Amato, Anthony, Richman

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 1.54 MB

english, 2014

25

A phase 1b clinical trial evaluating sifalimumab, an anti-IFN- monoclonal antibody, shows target neutralisation of a type I IFN signature in blood of dermatomyositis and polymyositis patients

Higgs, B. W., Zhu, W., Morehouse, C., White, W. I., Brohawn, P., Guo, X., Rebelatto, M., Le, C., Amato, A., Fiorentino, D., Greenberg, S. A., Drappa, J., Richman, L., Greth, W., Jallal, B., Yao, Y.

Journal:

Annals of the Rheumatic Diseases

Year:

2014

Language:

english

File:

PDF, 2.25 MB

english, 2014

26

Avian Sulfhydryl Oxidase Is Not a Metalloenzyme: Adventitious Binding of Divalent Metal Ions to the Enzyme †

Brohawn, Stephen G., Miksa, Irina Rudik, Thorpe, Colin

Journal:

Year:

2003

Language:

english

File:

PDF, 196 KB

english, 2003

27

MicroRNA-206 induces G1 arrest in melanoma by inhibition of CDK4 and Cyclin D

Georgantas, Robert W., Streicher, Katie, Luo, Xiaobing, Greenlees, Lydia, Zhu, Wei, Liu, Zheng, Brohawn, Philip, Morehouse, Christopher, Higgs, Brandon W., Richman, Laura, Jallal, Bahija, Yao, Yihong,

Journal:

Pigment Cell & Melanoma Research

Year:

2014

Language:

english

File:

PDF, 7.33 MB

english, 2014

28

Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel

Brohawn, Stephen G., Campbell, Ernest B., MacKinnon, Roderick

Journal:

Year:

2014

Language:

english

File:

PDF, 4.82 MB

english, 2014

29

Relationship between disease activity and type 1 interferon- and other cytokine-inducible gene expression in blood in dermatomyositis and polymyositis

Greenberg, S A, Higgs, B W, Morehouse, C, Walsh, R J, Won Kong, S, Brohawn, P, Zhu, W, Amato, A, Salajegheh, M, White, B, Kiener, P A, Jallal, B, Yao, Y

Journal:

Genes and Immunity

Year:

2012

Language:

english

File:

PDF, 532 KB

english, 2012

30

Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K + channels

Brohawn, Stephen G., Su, Zhenwei, MacKinnon, Roderick

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 2.05 MB

english, 2014

31

Homodimerization of the G protein SRbeta in the nucleotide-free state involves proline cis/trans isomerization in the switch II region

Schwartz, T. U., Schmidt, D., Brohawn, S. G., Blobel, G.

Journal:

Proceedings of the National Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 2.86 MB

english, 2006

32

The Plasma Cell Signature in Autoimmune Disease

Streicher, Katie, Morehouse, Christopher A., Groves, Christopher J., Rajan, Bhargavi, Pilataxi, Fernanda, Lehmann, Kim P., Brohawn, Philip Z., Higgs, Brandon W., McKeever, Kathleen, Greenberg, Steven

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 486 KB

english, 2014

33

Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel

Brohawn, S. G., Campbell, E. B., MacKinnon, R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 1.30 MB

english, 2013

34

Circulating Tumor Cells: Application as a Biomarker for Molecular Characterization and Predictor of Survival in an All-Comer Solid Tumor Phase I Clinical Study

Bao, Haifeng, Burke, Patricia A., Huang, Jiaqi, Chen, Xiaoru, Brohawn, Philip Z., Yao, Yihong, Lechleider, Robert J., Sikorski, Robert S., Buzoianu, Manuela, Zhang, Jianliang, Shi, Xiaoqing, Richman,

Journal:

Year:

2013

Language:

english

File:

PDF, 572 KB

english, 2013

35

Structural Evidence for Common Ancestry of the Nuclear Pore Complex and Vesicle Coats

Brohawn, S. G., Leksa, N. C., Spear, E. D., Rajashankar, K. R., Schwartz, T. U.

Journal:

Year:

2008

Language:

english

File:

PDF, 637 KB

english, 2008

36

Development and Validation of a Predictive Model for the Growth of Vibrio vulnificus in Postharvest Shellstock Oysters

DaSilva, L., Parveen, S., DePaola, A., Bowers, J., Brohawn, K., Tamplin, M. L.

Journal:

Applied and Environmental Microbiology

Year:

2012

Language:

english

File:

PDF, 639 KB

english, 2012

37

Development of Potential Pharmacodynamic and Diagnostic Markers for Anti-IFN-α Monoclonal Antibody Trials in Systemic Lupus Erythematosus

Yao, Yihong, Higgs, Brandon W., Morehouse, Chris, de los Reyes, Melissa, Trigona, Wendy, Brohawn, Philip, White, Wendy, Zhang, Jianliang, White, Barbara, Coyle, Anthony J., Kiener, Peter A., Jallal, B

Journal:

Human Genomics and Proteomics

Year:

2009

Language:

english

File:

PDF, 3.48 MB

english, 2009

38

Opposing Roles of Membrane and Soluble Forms of the Receptor for Advanced Glycation End Products in Primary Respiratory Syncytial Virus Infection

Miller, A. L., Sims, G. P., Brewah, Y. A., Rebelatto, M. C., Kearley, J., Benjamin, E., Keller, A. E., Brohawn, P., Herbst, R., Coyle, A. J., Humbles, A. A., Kolbeck, R.

Journal:

The Journal of Infectious Diseases

Year:

2012

Language:

english

File:

PDF, 853 KB

english, 2012

39

Analysis of time-course gene expression profiles to study regulation of cell growth in fed-batch bioreactors

Lin, Yanzhu, Lehmann, Kim, Brohawn, Philip Z., Liu, Zheng, Agarwal, Nitin

Journal:

Biochemical Engineering Journal

Year:

2015

Language:

english

File:

PDF, 1.59 MB

english, 2015

40

OP0255 Inhibition of the Plasma Cell Signature Correlates with Reduced Collagen Expression in Systemic Sclerosis

Streicher, K., Morehouse, C., Groves, C., Rajan, B., Pilataxi, F., Lehmann, K., Brohawn, P. Z., Higgs, B. W., McKeever, K., Richman, L., Jallal, B., Herbst, R., Yao, Y., Ranade, K.

Journal:

Annals of the Rheumatic Diseases

Year:

2013

Language:

english

File:

PDF, 282 KB

english, 2013

41

Synergistic Actions of Blocking Angiopoietin-2 and Tumor Necrosis Factor-α in Suppressing Remodeling of Blood Vessels and Lymphatics in Airway Inflammation

Le, Catherine T.K., Laidlaw, Grace, Morehouse, Christopher A., Naiman, Brian, Brohawn, Philip, Mustelin, Tomas, Connor, Jane R., McDonald, Donald M.

Journal:

The American Journal of Pathology

Year:

2015

Language:

english

File:

PDF, 7.47 MB

english, 2015

42

A high density of tertiary lymphoid structure B cells in lung tumors is associated with increased CD4 + T cell receptor repertoire clonality

Zhu, Wei, Germain, Claire, Liu, Zheng, Sebastian, Yinong, Devi, Priyanka, Knockaert, Samantha, Brohawn, Philip, Lehmann, Kim, Damotte, Diane, Validire, Pierre, Yao, Yihong, Valge-Archer, Viia, Hammond

Journal:

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

43

Neutrophils Regulate Humoral Autoimmunity by Restricting Interferon-γ Production via the Generation of Reactive Oxygen Species

Huang, Xinfang, Li, Jingjing, Dorta-Estremera, Stephanie, Di Domizio, Jeremy, Anthony, Scott M., Watowich, Stephanie S., Popkin, Daniel, Liu, Zheng, Brohawn, Philip, Yao, Yihong, Schluns, Kimberly S.,

Journal:

Year:

2015

Language:

english

File:

PDF, 2.90 MB

english, 2015

44

Climate relationships to fecal bacterial densities in Maryland shellfish harvest waters

Leight, A.K., Hood, R., Wood, R., Brohawn, K.

Journal:

Year:

2016

Language:

english

File:

PDF, 3.87 MB

english, 2016

45

SAT0212 Sustained Response to Mavrilimumab in Rheumatoid Arthritis Patients VIA Suppression of Macrophage and T Cells

Guo, X., Sinibaldi, D., Kuziora, M., Brohawn, P., Ryan, P.C., Bay-Jensen, A.C., Karsdal, M.A., Roskos, L.K., White, W.I.

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 83 KB

english, 2015

46

15LBA High tumoral IFNγ mRNA, PD-L1 protein, and combined IFNγ mRNA/PD-L1 protein expression associates with response to durvalumab (anti-PD-L1) monotherapy in NSCLC patients

Higgs, B.W., Robbins, P.B., Blake-Haskins, J.A., Zhu, W., Morehouse, C., Brohawn, P.Z., Rebelatto, M.C., Yao, Y., Jin, X., Shi, L., Ranade, K.

Journal:

European Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 65 KB

english, 2015

47

A lattice model of the nuclear pore complex

Brohawn, Stephen G., Schwartz, Thomas U.

Journal:

Communicative & Integrative Biology

Year:

2009

Language:

english

File:

PDF, 1.00 MB

english, 2009

48

Type I IFNs Regulate Inflammation, Vasculopathy, and Fibrosis in Chronic Cutaneous Graft-versus-Host Disease

Delaney, T. A., Morehouse, C., Brohawn, P. Z., Groves, C., Colonna, M., Yao, Y., Sanjuan, M., Coyle, A. J.

Journal:

The Journal of Immunology

Year:

2016

Language:

english

File:

PDF, 1.66 MB

english, 2016

49

HERC5is a prognostic biomarker for post-liver transplant recurrent human hepatocellular carcinoma

Xue, Feng, Higgs, Brandon W., Huang, Jiaqi, Morehouse, Chris, Zhu, Wei, Yao, Xin, Brohawn, Philip, Xiao, Zhan, Sebastian, Yinong, Liu, Zheng, Xia, Yun, Shen, Dong, Kuziora, Mike, Dong, Zhengwei, Han,

Journal:

Journal of Translational Medicine

Year:

2015

Language:

english

File:

PDF, 3.45 MB

english, 2015

50

In Vivo Therapeutic Success of MicroRNA-155 Antagomir in a Mouse Model of Lupus Alveolar Hemorrhage

Zhou, Shiyu, Wang, Yan, Meng, Yao, Xiao, Chunyuan, Liu, Zheng, Brohawn, Philip, Higgs, Brandon W., Jallal, Bahija, Jia, Qian, Qu, Bo, Huang, Xinfang, Tang, Yuanjia, Yao, Yihong, Harley, John B., Shen,

Journal:

Arthritis & Rheumatology

Year:

2016

Language:

english

File:

PDF, 679 KB

english, 2016

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